Dorsal Hippocampus ERK2 Signaling Mediates Anxiolytic-Related Behavior in Male Rats
نویسندگان
چکیده
منابع مشابه
Anxiolytic Treatment Impairs Helping Behavior in Rats
Despite decades of research with humans, the biological mechanisms that motivate an individual to help others remain poorly understood. In order to investigate the roots of pro-sociality in mammals, we established the helping behavior test, a paradigm in which rats are faced with a conspecific trapped in a restrainer that can only be opened from the outside. Over the course of repeated test ses...
متن کاملStudy of Anticonvulsant Effects of Carbamazepine During Epileptic Process by Unilateral Kindling of CA1 Dorsal Hippocampus in Adult Male Rats
Introduction: Epilepsy is a chronic and multifactorial disease with recurrent seizures. Carbamazepine is the most common drug used to treat epilepsy. In this research project, the anticonvulsant effects of carbamazepine on the seizure parameters in adult male rats during dorsal hippocampal are investigated epilepsy by electrical kindling method. Methods: This study is experimental. In this stu...
متن کاملRole of acetylcholine and dopamine in dorsal hippocampus on hoarding behavior in rats.
The probable roles of Acetylcholine (Ach) and Dopamine (DA) in the modulation of instinctual behaviors of feeding and hoarding (HS), as also the body weight and vaginal cyclicity (EI), were studied by instillation of Atropine (Ach antagonist), Haloperidol (DA antagonist) and Apomorphine (DA agonist) in the dorsal hippocampus of nonpregnant female rats. It was observed that the HS was significan...
متن کاملAnxiolytic Effect of Borago officinalis (Boraginaceae) Extract in Male Rats
Background: Medicinal plants with natural antioxidants have been shown to be beneficial in a variety of complications such as anxiety. The elevated plus-maze (EPM) is one of the most widely used models to assess anxiety in small rodents. Objectives: This study was designed to characterize the anxiolytic-like activity of Borago officinalis (Linnaeus, family Boraginaceae) or Borage flowers extrac...
متن کاملEndocannabinoid System and TRPV1 Receptors in the Dorsal Hippocampus of the Rats Modulate Anxiety-like Behaviors
Objective(s) Fatty acid is amide hydrolase which reduce endogenous anandamide. Transient receptor potential vanilloid-1 (TRPV1) channels have been reported to have a role in the modulation of anxiety-like behaviors in rodents. In the present study, the effects of either endocannabinoid system or TRPV1 channels and their possible interaction on anxiety-like behaviors of the rats were explored. ...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Chronic Stress
سال: 2019
ISSN: 2470-5470,2470-5470
DOI: 10.1177/2470547019897030